SCHEMBL7595668

SCHEMBL7595668

C=Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.54
TSHR P16473 2/20 0.46
LMNA P02545 2/20 0.46
VCAM1 P19320 1/20 0.45
CYP3A4 P08684 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 2/20 0.43
NFE2L2 Q16236 2/20 0.42
FBP1 P09467 3/20 0.41
VCP P55072 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HTT P42858 2/20 0.40
APP P05067 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5882248 0.87 XDH (0.42) CYP19A1TSHRLMNAVCAM1ALDH1A1
SCHEMBL16951430 0.86 CYP19A1 (0.40) CYP19A1TSHRLMNACYP3A4ALDH1A1
SCHEMBL16959336 0.86 TSHR (0.63) CYP19A1TSHRLMNACYP3A4ALDH1A1
SCHEMBL16955664 0.86 LMNA (0.42) CYP19A1TSHRLMNAVCAM1CYP3A4
SCHEMBL13228708 0.86 ALDH1A1 (0.46) CYP19A1TSHRALDH1A1NFE2L2FBP1
SCHEMBL22426071 0.86 AMY1A (0.53) CYP19A1TSHRLMNASMN1; SMN2ALDH1A1
SCHEMBL8418032 0.84 CYP19A1 (0.39) CYP19A1TSHRLMNAVCAM1CYP3A4
SCHEMBL27969972 0.83 TSHR (0.56) CYP19A1TSHRLMNAALDH1A1NFE2L2
SCHEMBL8418034 0.82 TSHR (0.50) CYP19A1TSHRLMNAVCAM1CYP3A4
SCHEMBL3130397 0.81 TP53 (0.50) LMNACYP3A4SMN1; SMN2ALDH1A1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117866000-B Diamine monomer with nitrogen heterocycle and siloxane structure, and preparation method and application thereof 波米科技有限公司 2024-06-21 CN claimed
CN-117866000-A Diamine monomer with nitrogen heterocycle and siloxane structure, and preparation method and application thereof 波米科技有限公司 2024-04-12 CN claimed
CN-117866000-B Diamine monomer with nitrogen heterocycle and siloxane structure, and preparation method and application thereof 波米科技有限公司 2024-06-21 CN disclosed
CN-117866000-A Diamine monomer with nitrogen heterocycle and siloxane structure, and preparation method and application thereof 波米科技有限公司 2024-04-12 CN disclosed
US-9927708-B2 Pattern forming process and shrink agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-27 US disclosed
US-9658532-B2 Pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-23 US disclosed
US-9658532-B2 Pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-23 US disclosed
US-9632415-B2 Pattern forming process and shrink agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-25 US disclosed
US-9632415-B2 Pattern forming process and shrink agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-25 US disclosed
US-9618850-B2 Pattern forming process and shrink agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-11 US disclosed
US-9618850-B2 Pattern forming process and shrink agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-11 US disclosed
US-20160124312-A1 PATTERN FORMING PROCESS AND SHRINK AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-05-05 US disclosed
US-20160124312-A1 PATTERN FORMING PROCESS AND SHRINK AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-05-05 US disclosed
US-20160124313-A1 PATTERN FORMING PROCESS AND SHRINK AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-05-05 US disclosed
US-6448442-B1 X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS AMERSHAM HEALTH AS (NO) 2002-09-10 US disclosed
US-6310243-B1 BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY NYCOMED IMAGING AS (NO) 2001-10-30 US disclosed
US-5993780-A A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE NYCOMED IMAGING AS (NO) 1999-11-30 US disclosed
US-5882628-A Contrast media NYCOMED IMAGING AS (NO) 1999-03-16 US disclosed
EP-0782564-A1 IODINATED X-RAY CONTRAST MEDIA NYCOMED IMAGING AS (NO) 1997-07-09 EP disclosed
WO-1996009282-A1 IODINATED X-RAY CONTRAST MEDIA NYCOMED IMAGING A/S (NO) 1996-03-28 WO disclosed