Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28712690 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL7829657 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL5256102 | 0.79 | LOXL2 (0.60) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL7835431 | 0.77 | SMN1; SMN2 (0.89) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL7835167 | 0.77 | SMN1; SMN2 (0.89) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL9179542 | 0.77 | POLB (0.56) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL27953694 | 0.77 | HPGD (0.50) | SMN1; SMN2ALOX15HPGDPOLBHSD17B10 | |
| Methane SCHEMBL7997331 | 0.76 | SMN1; SMN2 (0.86) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| Octanedioate SCHEMBL30132328 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL9305220 | 0.76 | POLB (0.57) | SMN1; SMN2ALOX15HTTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747448-B1 | Rigidized monomethine cyanine dyes | UNIV CARNEGIE MELLON (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-0747448-A2 | Rigidized monomethine cyanine dyes | CARNEGIE-MELLON UNIVERSITY (US) | 1996-12-11 | — | — | EP | disclosed |