Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7600878 | 0.99 | TRPM8 (0.41) | TRPM8NPY1RNPY5RCNR1CNR2 | |
| SCHEMBL7600674 | 0.94 | TRPM8 (0.46) | TRPM8ALOX5HTR2AHRH1MDM2 | |
| Hydrochloric Acid SCHEMBL7594995 | 0.93 | TRPM8 (0.45) | TRPM8ALOX5HTR2AHRH1MDM2 | |
| SCHEMBL7600460 | 0.90 | MEN1 (0.42) | TRPM8CNR1CNR2ALOX5HTR2A | |
| SCHEMBL7596315 | 0.90 | MEN1 (0.42) | TRPM8CNR1CNR2ALOX5HTR2A | |
| Hydrochloric Acid SCHEMBL7600663 | 0.90 | TRPM8 (0.41) | TRPM8ALOX5HTR2AHRH1MDM2 | |
| Hydrochloric Acid SCHEMBL7600447 | 0.88 | ALOX5 (0.42) | TRPM8NPY5RALOX5 | |
| SCHEMBL7597931 | 0.88 | ALDH1A1 (0.44) | TRPM8CNR1CNR2ALOX5 | |
| SCHEMBL7595296 | 0.88 | ALDH1A1 (0.44) | TRPM8CNR1CNR2ALOX5 | |
| Hydrochloric Acid SCHEMBL7600168 | 0.87 | ALDH1A1 (0.46) | TRPM8CNR1CNR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |