Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600399 | 0.87 | HSD17B10 (0.40) | KYNUACE2MMP1CTSKHSD17B10 | |
| SCHEMBL7600401 | 0.86 | HSD17B10 (0.51) | MMP1MMP3HSD17B10 | |
| SCHEMBL7602466 | 0.84 | MMP1 (0.55) | ACE2MMP1MMP3CTSKHSD17B10 | |
| SCHEMBL9698601 | 0.83 | HSD17B10 (0.56) | KYNUACE2MMP1MMP3CTSK | |
| SCHEMBL7403327 | 0.83 | CTSK (0.58) | CTSKCTSLCTSBCTSS | |
| SCHEMBL8639837 | 0.81 | GPR88 (0.37) | MMP1CTSB | |
| SCHEMBL8752163 | 0.79 | GPR88 (0.37) | MMP1HSD17B10CTSB | |
| SCHEMBL7598874 | 0.79 | HSD17B10 (0.62) | ACE2MMP1MMP3HSD17B10MME | |
| Hydrochloric Acid SCHEMBL6926940 | 0.78 | GPR88 (0.37) | MMP1HSD17B10CTSB | |
| SCHEMBL8641877 | 0.78 | GPR88 (0.36) | MMP1MMP3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |
| US-5716943-A | CARDIOVASCULAR DISORDERS | ZAMBON GROUP. S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |