Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | KYNU | Q16719 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639837 | 0.89 | GPR88 (0.37) | GPR88CTSBMEN1KMT2AF2 | |
| SCHEMBL7596669 | 0.87 | KYNU (0.45) | HSD17B10KYNUCTSKCTSLCTSB | |
| SCHEMBL7599732 | 0.86 | F10 (0.35) | GPR88KYNUF2F10PRSS1 | |
| SCHEMBL7598917 | 0.85 | HSD17B10 (0.37) | HSD17B10GPR88MEN1KMT2AACE2 | |
| SCHEMBL7600401 | 0.83 | HSD17B10 (0.51) | HSD17B10MMP1 | |
| SCHEMBL7598876 | 0.83 | ACE2 (0.44) | HSD17B10ACE2MMEECE1 | |
| SCHEMBL8752163 | 0.82 | GPR88 (0.37) | HSD17B10GPR88CTSBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6926940 | 0.81 | GPR88 (0.37) | HSD17B10GPR88CTSBF2F10 | |
| SCHEMBL8641877 | 0.79 | GPR88 (0.36) | HSD17B10GPR88ANPEPMMP1 | |
| SCHEMBL8641846 | 0.78 | MMP3 (0.36) | HSD17B10GPR88F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |
| EP-0766687-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |