Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760535 | 0.92 | ESR1 (0.51) | HSD17B10KMT2AMEN1NPC1TLR9 | |
| SCHEMBL14276111 | 0.81 | CYP3A4 (0.50) | KMT2AMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL11299180 | 0.81 | CYP3A4 (0.50) | KMT2AMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL14877646 | 0.79 | HSD17B10 (0.68) | HSD17B10KMT2AMEN1NPC1TLR9 | |
| SCHEMBL759685 | 0.79 | NPSR1 (0.47) | HSD17B10KMT2AMEN1NPC1TLR9 | |
| SCHEMBL14682218 | 0.77 | BACE1 (0.49) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL15417137 | 0.77 | BACE1 (0.49) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13986166 | 0.77 | BACE1 (0.49) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10015730 | 0.77 | BACE1 (0.49) | HSD17B10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL12639229 | 0.76 | MGLL (0.57) | HSD17B10KMT2AMEN1ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426092-B2 | Poly(imide-carbonate) polytetrafluoroethylene containing photoconductors | XEROX CORPORATION (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120070769-A1 | INTERMEDIATE TRANSFER MEMBER | XEROX CORPORATION (US) | 2012-03-22 | — | — | US | disclosed |
| US-8138300-B1 | Intermediate transfer member | XEROX CORPORATION (US) | 2012-03-20 | — | — | US | disclosed |
| US-20120052426-A1 | POLY(IMIDE-CARBONATE) POLYTETRAFLUOROETHYLENE CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2012-03-01 | — | — | US | disclosed |