Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760421 | 0.91 | NPSR1 (0.54) | NPSR1CYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL14276111 | 0.85 | CYP3A4 (0.50) | CYP3A4TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL11299180 | 0.85 | CYP3A4 (0.50) | CYP3A4TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL759682 | 0.81 | NPSR1 (0.43) | NPSR1CYP3A4TP53KMT2AMEN1 | |
| SCHEMBL12603929 | 0.80 | LMNA (0.47) | NPSR1KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL759684 | 0.79 | HSD17B10 (0.54) | KMT2AMEN1ALDH1A1HSD17B10LMNA | |
| SCHEMBL14877711 | 0.76 | NPSR1 (0.54) | NPSR1CYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL13526136 | 0.76 | POLB (0.45) | NPSR1HTTPOLBLMNAMAPT | |
| SCHEMBL14682218 | 0.76 | BACE1 (0.49) | CYP3A4KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL13986166 | 0.76 | BACE1 (0.49) | CYP3A4KMT2AMEN1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426092-B2 | Poly(imide-carbonate) polytetrafluoroethylene containing photoconductors | XEROX CORPORATION (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120070769-A1 | INTERMEDIATE TRANSFER MEMBER | XEROX CORPORATION (US) | 2012-03-22 | — | — | US | disclosed |
| US-8138300-B1 | Intermediate transfer member | XEROX CORPORATION (US) | 2012-03-20 | — | — | US | disclosed |
| US-20120052426-A1 | POLY(IMIDE-CARBONATE) POLYTETRAFLUOROETHYLENE CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2012-03-01 | — | — | US | disclosed |