SCHEMBL7597089

SCHEMBL7597089

CC1=Cc2c(cccc2-c2cccc3ccccc23)[C]1CC[C]1C(C)=Cc2c1cccc2-c1cccc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
CYP2A6 P11509 1/20 0.38
DHFR P00374 1/20 0.36
PTPN1 P18031 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
KDM4E B2RXH2 4/20 0.35
ENPP3 O14638 1/20 0.35
ENPP1 P22413 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
HPGD P15428 2/20 0.34
CNR1 P21554 2/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX5 P09917 1/20 0.33
CYP11B2 P19099 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7595974 0.74 HTR7 (0.33) ALDH1A1CYP2A6CA1CA2CA9
SCHEMBL5487945 0.73 ALDH1A1 (0.56) ALDH1A1CYP2A6PTPN1KDM4EHPGD
SCHEMBL25302086 0.71 ALDH1A1 (0.59) ALDH1A1CYP2A6PTPN1KDM4ECA12
SCHEMBL29350007 0.71 ALDH1A1 (0.59) ALDH1A1CYP2A6PTPN1KDM4ECA12
SCHEMBL27953 0.71 ALDH1A1 (0.59) ALDH1A1CYP2A6PTPN1KDM4ECA12
SCHEMBL7598196 0.69 GABRA1 (0.37) CA12CA1CA2CA9HPGD
Bromide SCHEMBL8588309 0.69 ALDH1A1 (0.56) ALDH1A1CYP2A6PTPN1KDM4ECA12
Hydrochloric Acid SCHEMBL4268575 0.69 ALDH1A1 (0.56) ALDH1A1CYP2A6PTPN1KDM4EHPGD
Ammonia Solution, Strong SCHEMBL3156160 0.69 ALDH1A1 (0.56) ALDH1A1CYP2A6PTPN1KDM4ECA12
SCHEMBL18174178 0.69 ALDH1A1 (0.56) ALDH1A1CYP2A6PTPN1KDM4ECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020052446-A1 Composition based on monofluorometal complexes BAYER AKTIENGESELLSCHAFT (DE) 2002-05-02 US disclosed
US-5965678-A Catalyst system based on monoazadiene metal complexes BAYER AG (DE) 1999-10-12 US disclosed