Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597777 | 1.00 | CNR1 (0.43) | CNR1CNR2MEN1KMT2AALOX5 | |
| SCHEMBL7595142 | 0.94 | TRPM8 (0.41) | CNR1CNR2ALOX5TRPM8 | |
| SCHEMBL7595802 | 0.94 | TRPM8 (0.41) | CNR1CNR2ALOX5TRPM8 | |
| SCHEMBL28032819 | 0.91 | CNR1 (0.42) | CNR1CNR2TRPM8 | |
| SCHEMBL7598351 | 0.91 | CNR1 (0.42) | CNR1CNR2TRPM8 | |
| SCHEMBL7596200 | 0.91 | TRPM8 (0.37) | CNR1CNR2ALOX5TRPM8 | |
| SCHEMBL1382274 | 0.91 | CNR1 (0.42) | CNR1CNR2TRPM8 | |
| SCHEMBL7597372 | 0.89 | F2 (0.40) | CNR1CNR2ALOX5TRPM8 | |
| SCHEMBL7595822 | 0.88 | CNR1 (0.47) | CNR1CNR2KMT2AALOX5TRPM8 | |
| SCHEMBL7600642 | 0.88 | ITGB3 (0.36) | CNR1CNR2MEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | claimed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | claimed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |