Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596641 | 0.93 | CNR1 (0.47) | ALOX5CNR1CNR2TRPM8BMP1 | |
| SCHEMBL7595822 | 0.93 | CNR1 (0.47) | ALOX5CNR1CNR2TRPM8BMP1 | |
| SCHEMBL7595142 | 0.93 | TRPM8 (0.41) | ALOX5CNR1CNR2TRPM8 | |
| SCHEMBL7595802 | 0.93 | TRPM8 (0.41) | ALOX5CNR1CNR2TRPM8 | |
| SCHEMBL7596200 | 0.90 | TRPM8 (0.37) | ALOX5CNR1CNR2TRPM8SMN1; SMN2 | |
| SCHEMBL1382274 | 0.90 | CNR1 (0.42) | CNR1CNR2TRPM8NPY5R | |
| SCHEMBL7598351 | 0.90 | CNR1 (0.42) | CNR1CNR2TRPM8NPY5R | |
| SCHEMBL28032819 | 0.90 | CNR1 (0.42) | CNR1CNR2TRPM8NPY5R | |
| SCHEMBL7596920 | 0.90 | ALOX5 (0.50) | F7ALOX5EPORACACBNPY5R | |
| SCHEMBL7597379 | 0.89 | CNR1 (0.43) | ALOX5CNR1CNR2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | claimed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |