Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.54 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932413 | 0.84 | LMNA (0.55) | L3MBTL1L3MBTL3MBTD1KDM4ELMNA | |
| SCHEMBL30839226 | 0.83 | KDM1A (0.48) | L3MBTL1L3MBTL3MBTD1CYP2C19KDM4E | |
| SCHEMBL30730934 | 0.83 | ACHE (0.42) | L3MBTL1L3MBTL3MBTD1KDM4ELMNA | |
| SCHEMBL7627201 | 0.81 | KDM1A (0.53) | CYP2D6CYP2C19KDM4EGAALMNA | |
| SCHEMBL73610 | 0.81 | KDM1A (0.53) | CYP2D6CYP2C19KDM4EGAALMNA | |
| SCHEMBL17911056 | 0.81 | KDM1A (0.53) | CYP2D6CYP2C19KDM4EGAALMNA | |
| SCHEMBL1752645 | 0.79 | KDM1A (0.50) | L3MBTL1CYP2D6CYP2C19KDM4EGAA | |
| SCHEMBL30918138 | 0.78 | KDM4E (0.46) | L3MBTL1L3MBTL3MBTD1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL19996083 | 0.77 | KDM1A (0.48) | L3MBTL1CYP2D6CYP2C19KDM4EGAA | |
| SCHEMBL31053522 | 0.76 | TDP1 (0.38) | L3MBTL1CYP2C19KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103709172-B | Substituted furan and piperidine derivative and its application | 江苏先声药业有限公司 | 2018-02-13 | — | — | CN | disclosed |
| WO-2002099388-A2 | BENZODIAZEPINE BRADYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 2002-12-12 | — | — | WO | disclosed |