Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911056 | 1.00 | KDM1A (0.53) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL7627201 | 1.00 | KDM1A (0.53) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL1752645 | 0.98 | KDM1A (0.50) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL19996083 | 0.95 | KDM1A (0.48) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL1829575 | 0.93 | KDM1A (0.46) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL4055295 | 0.87 | ALDH1A1 (0.43) | KDM1AALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL3544482 | 0.84 | POLB (0.44) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL7597635 | 0.81 | L3MBTL1 (0.54) | ALDH1A1CYP2C19LMNAGAAKDM4E | |
| SCHEMBL6626303 | 0.80 | POLB (0.44) | KDM1AALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL644787 | 0.77 | POLB (0.49) | ALDH1A1CYP1A2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262320-A | Synthesis method for preparing anilinopiperidine drugs by using continuous flow microchannel reactor | 宜昌人福药业有限责任公司 | 2022-04-01 | — | — | CN | claimed |
| US-20160271248-A1 | CXCR4 UP- AND DOWN-REGULATION FOR TREATMENT OF DISEASES OR DISORDERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-09-22 | — | — | US | claimed |
| WO-2016115013-A1 | CINNOLINE DERIVATIVES USEFUL AS CB-1 RECEPTOR INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-21 | — | — | WO | claimed |
| WO-2015051279-A2 | CXCR4 UP- AND DOWN-REGULATION FOR TREATMENT OF DISEASES OR DISORDERS | DREXEL UNIVERSITY (US) | 2015-04-09 | — | — | WO | claimed |
| EP-2318363-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | Nuevolution A/S (DK) | 2011-05-11 | — | — | EP | claimed |
| US-20100144591-A1 | BENZIMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION | 2010-06-10 | — | — | US | claimed |
| US-20100093692-A1 | PIPERIDINYL-PIPERIDINE AND PIPERAZINYL-PIPERIDINE FOR USE IN THE TREATMENT OF DIABETES OR PAIN | SCHERING CORPORATION SECHERING-PLOUGH CORPORATION (US) | 2010-04-15 | — | — | US | claimed |
| CN-101674831-A | Piperidinylpiperidine and piperazinylpiperidine for the treatment of diabetes or pain | SCHERING CORP | 2010-03-17 | — | — | CN | claimed |
| EP-2136805-A2 | PIPERIDINYL-PIPERIDINE AND PIPERAZINYL-PIPERIDINE FOR USE IN THE TREATMENT OF DIABETES OR PAIN | SCHERING CORPORATION (US) | 2009-12-30 | — | — | EP | claimed |
| WO-2009152824-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2009-12-23 | — | — | WO | claimed |
| EP-2114402-A2 | BENZIMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2009-11-11 | — | — | EP | claimed |
| WO-2008108957-A2 | PIPERIDINYL-PIPERIDINE AND PIPERAZINYL-PIPERIDINE FOR USE IN THE TREATMENT OF DIABETES OR PAIN | SCHERING CORPORATION (US) | 2008-09-12 | — | — | WO | claimed |
| WO-2008108958-A2 | BENZIMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-09-12 | — | — | WO | claimed |
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | claimed |
| EP-0523125-A1 | NOVEL PIPERIDIN-4-SPIRO-OXIRANES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1993-01-20 | — | — | EP | claimed |
| US-5175174-A | PHENYLPIPERIDINYLAMINES AND DRUGS CONTAINING THESE | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-29 | — | — | US | claimed |
| WO-1991015492-A1 | NOVEL PIPERIDIN-4-SPIRO-OXIRANES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1991-10-17 | — | — | WO | claimed |
| US-4831192-A | Methods of preparing 4-heteropentacyclic-4-(N-phenyl)amido) piperidine derivatives and intermediate compounds | BOC, INC. (US) | 1989-05-16 | — | — | US | claimed |
| JP-1301676-A | — | — | None | — | — | JP | disclosed |
| EP-0095722-B1 | COLOR PHOTOGRAPHIC MATERIALS | KONICA CORPORATION (JP) | 1987-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093692-A1 | PIPERIDINYL-PIPERIDINE AND PIPERAZINYL-PIPERIDINE FOR USE IN THE TREATMENT OF DIABETES OR PAIN | GPR119, ATF4, GID4 | KDM1A 3192/4885ALDH1A1 564/4885CYP1A2 2201/4885 |
| US-20100144591-A1 | BENZIMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF | GPR119, GK, GCK | KDM1A 3122/4885ALDH1A1 612/4885CYP1A2 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.