Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911056 | 1.00 | KDM1A (0.53) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL73610 | 1.00 | KDM1A (0.53) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL1752645 | 0.98 | KDM1A (0.50) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL19996083 | 0.95 | KDM1A (0.48) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL1829575 | 0.93 | KDM1A (0.46) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL4055295 | 0.87 | ALDH1A1 (0.43) | KDM1AALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL3544482 | 0.84 | POLB (0.44) | KDM1AALDH1A1CYP1A2CYP2C19HTT | |
| SCHEMBL7597635 | 0.81 | L3MBTL1 (0.54) | ALDH1A1CYP2C19LMNAGAAKDM4E | |
| SCHEMBL6626303 | 0.80 | POLB (0.44) | KDM1AALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL644787 | 0.77 | POLB (0.49) | ALDH1A1CYP1A2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237935-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | Bridgestone Corporation (JP) | 2002-09-11 | — | — | EP | claimed |
| WO-2001034659-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | BRIDGESTONE CORPORATION (JP) | 2001-05-17 | — | — | WO | claimed |