Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969445 | 0.86 | PRMT3 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL557874 | 0.76 | PRMT3 (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL28156458 | 0.76 | PRMT3 (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL20873462 | 0.75 | HPGD (0.37) | HTR2AHRH1DNM1USP2 | |
| SCHEMBL24693927 | 0.75 | PIK3CD (0.30) | — | |
| SCHEMBL10290497 | 0.73 | LMNA (0.57) | — | |
| SCHEMBL21765434 | 0.73 | LMNA (0.57) | — | |
| SCHEMBL10290383 | 0.73 | LMNA (0.57) | — | |
| SCHEMBL5949186 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRHTR2AHRH1DNM1 | |
| SCHEMBL13443141 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962447-B1 | Process for the preparation of secondary or tertiary 2-methyl-1,5-pentanediamines | BASF AG (DE) | 2002-12-18 | — | — | EP | disclosed |
| US-6198002-B1 | REACTING 2-METHYLGLUTARONITRILE WITH PRIMARY OR SECONDARY AMINE AND HYDROGEN IN PRESENCE OF OXIDIC SUPPORTED CATALYST COMPRISING ONE OR MORE NOBLE METALS WHICH HAS BEEN TREATED WITH HYDROGEN | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| EP-0962447-A2 | Process for the preparation of secondary or tertiary 2-methyl-1,5-pentanediamines | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-08 | — | — | EP | disclosed |