SCHEMBL557874

SCHEMBL557874

CNCC(CCCN(C)C)N(C)C

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.37
CARM1 Q86X55 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
PRMT1 Q99873 1/20 0.37
PRMT8 Q9NR22 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35
DNM1 Q05193 3/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20835084 0.94 ALDH1A1 (0.40) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL31442725 0.86 PRMT3 (0.40) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL5608083 0.81 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL16752102 0.78 TDP1 (0.30) TDP1
SCHEMBL9385386 0.78 OPRD1 (0.33)
SCHEMBL30417749 0.77 ALDH1A1 (0.50) ALDH1A1TSHRHTR2AHRH1DNM1
SCHEMBL30761776 0.77 ALDH1A1 (0.43) ALDH1A1TSHRHTR2AHRH1DNM1
SCHEMBL7597772 0.76 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL13397769 0.75 OPRD1 (0.36) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL14392136 0.75 OPRD1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10464056-B2 Latent catalyst for the production of polyurethane foam MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-11-05 US claimed
US-20170225158-A1 LATENT CATALYST FOR THE PRODUCTION OF POLYURETHANE FOAM MOMENTIVE PERFORMANCE MATERIALS INC. 2017-08-10 US claimed
EP-3191535-A1 LATENT CATALYST FOR THE PRODUCTION OF POLYURETHANE FOAM Momentive Performance Materials Inc. (US) 2017-07-19 EP claimed
WO-2016039856-A1 LATENT CATALYST FOR THE PRODUCTION OF POLYURETHANE FOAM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-03-17 WO claimed
US-8877825-B2 Catalyst composition for production of polyurethane resin and method for producing polyurethane resin TOSOH CORPORATION (JP) 2014-11-04 US claimed
EP-2050775-B1 CATALYST COMPOSITION FOR POLYURETHANE RESIN PRODUCTION AND METHOD FOR PRODUCING POLYURETHANE RESIN TOSOH CORP (JP) 2013-08-14 EP claimed
US-20100130629-A1 CATALYST COMPOSITION FOR PRODUCTION OF POLYURETHANE RESIN AND METHOD FOR PRODUCING POLYURETHANE RESIN (AS AMENDED) TOSOH CORPORATION (JP) 2010-05-27 US claimed
EP-2050775-A1 CATALYST COMPOSITION FOR POLYURETHANE RESIN PRODUCTION AND METHOD FOR PRODUCING POLYURETHANE RESIN Tosoh Corporation (JP) 2009-04-22 EP claimed
EP-0989146-B1 Catalyst for production of polyurethane TOSOH CORP (JP) 2005-08-10 EP claimed
US-6384177-B1 QUATERNARY AMMONIUM CARBONATE OR CARBOXYLATE CATALYST; FLEXIBLE FOAMS; LOW ODOR AND CORROSIVENESS; HIGH FIRE RETARDANCE, CURABILITY, AND RETARDING EFFECT TOSOH CORPORATION (JP) 2002-05-07 US claimed
US-6384097-B1 HAVING LESS ODOR, AND PRODUCING FOAMS OF HIGH FIRE RETARDANCE, HAVING HIGH CURABILITY, HIGH RETARDING EFFECT, AND LOW CORROSIVENESS. TOSOH CORPORATION (JP) 2002-05-07 US claimed
US-20240239947-A1 THERMOSETTING COMPOSITION, POLYURETHANE RESIN COMPOSITION AND POLYURETHANE MOLDED BODY IDEMITSU KOSAN CO.,LTD. (JP) 2024-07-18 US disclosed
EP-4397492-A1 ADHESIVE, LAYERED BODY, METHOD FOR MANUFACTURING LAYERED BODY, AND PACKAGING MATERIAL DIC Corporation (JP) 2024-07-10 EP disclosed
WO-2024135376-A1 RECYCLED PLASTIC, PELLET, AND MOLDED BODY DIC株式会社 2024-06-27 WO disclosed
WO-2024135514-A1 TWO-PART CURABLE ADHESIVE, MULTILAYER BODY AND PACKAGE DIC株式会社 2024-06-27 WO disclosed
EP-0210440-B1 CATALYST FOR PRODUCING POLYURETHANE FOAMS COATED WITH A SKIN Tosoh Corporation (JP) 1991-12-11 EP disclosed
EP-0451826-A2 Process for producing flexible polyurethane foam having high air flow property Tosoh Corporation (JP) 1991-10-16 EP disclosed
US-4701473-A 4-METHYL-1-(2-HYDROXYALKYL)-PIPERAZINE TOYO SODA MANUFACTURING CO., LTD. (JP) 1987-10-20 US disclosed
US-4638016-A Process for producing high density elastic polyurethane using a combination of 4-methyl-1-(2-dimethylaminoethyl) piperazine together with another tertiary amine catalyst TOYA SODA MANUFACTURING CO., LTD. (JP) 1987-01-20 US disclosed
EP-0175927-A2 Process for producing elastomeric polyurethane foams of reduced weight Tosoh Corporation (JP) 1986-04-02 EP disclosed