Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600552 | 0.88 | DRD2 (0.33) | SLC6A4DRD2HTR7 | |
| SCHEMBL7597079 | 0.88 | DRD2 (0.33) | SLC6A4DRD2HTR7 | |
| SCHEMBL796750 | 0.86 | CNR2 (0.35) | SLC6A4DRD2HTR7CNR2TLR8 | |
| SCHEMBL797387 | 0.82 | CNR2 (0.33) | SLC6A4DRD2HTR7CNR2TLR8 | |
| SCHEMBL797770 | 0.81 | CNR2 (0.33) | SLC6A4DRD2HTR7CNR2TLR8 | |
| SCHEMBL5859330 | 0.80 | SLC6A4 (0.34) | SLC6A4DRD2HTR7CNR2HTR1A | |
| SCHEMBL8613248 | 0.79 | SLC6A4 (0.34) | SLC6A4DRD2HTR7CNR2HTR1A | |
| SCHEMBL27559648 | 0.79 | SLC6A4 (0.33) | SLC6A4DRD2HTR7CNR2HTR1A | |
| SCHEMBL4622630 | 0.79 | SLC6A4 (0.34) | SLC6A4DRD2HTR7CNR2HTR1A | |
| Hydrochloric Acid SCHEMBL4065888 | 0.77 | HTR7 (0.35) | SLC6A4DRD2HTR7CNR2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |