Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998523 | 0.87 | MEN1 (0.31) | SLC6A4SLC6A2SLC6A3CYP2D6MAPT | |
| SCHEMBL7188581 | 0.85 | ALOX15 (0.31) | SLC6A4MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL5859330 | 0.84 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3CYP2D6MAPT | |
| SCHEMBL8613248 | 0.83 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3CYP2D6MAPT | |
| SCHEMBL27559648 | 0.83 | SLC6A4 (0.33) | SLC6A4SLC6A2SLC6A3CYP2D6MAPT | |
| SCHEMBL4622950 | 0.82 | ALDH1A1 (0.36) | SLC6A4SLC6A2SLC6A3CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL4065888 | 0.82 | HTR7 (0.35) | SLC6A4SLC6A2SLC6A3CYP2D6MAPT | |
| SCHEMBL135958 | 0.81 | HTR7 (0.31) | SLC6A4SLC6A2SLC6A3CYP2D6HTR7 | |
| Hydrochloric Acid SCHEMBL4659081 | 0.81 | SLC6A4 (0.33) | SLC6A4SLC6A2SLC6A3CYP2D6ALDH1A1 | |
| SCHEMBL3996671 | 0.81 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219657-B1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-03-19 | — | — | EP | disclosed |