Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599783 | 0.89 | ESR1 (0.44) | LMNACYP3A4POLBRAB9AALDH1A1 | |
| SCHEMBL6326502 | 0.86 | PARP1 (0.43) | CYP3A4CYP2C19POLBALDH1A1TP53 | |
| SCHEMBL20981709 | 0.79 | HCRTR2 (0.43) | POLBHCRTR2MAPK1NSD2ESR1 | |
| SCHEMBL28293337 | 0.78 | LMNA (0.42) | LMNANPSR1POLBALDH1A1TP53 | |
| SCHEMBL29430026 | 0.78 | STS (0.49) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7597834 | 0.77 | LMNA (0.51) | LMNAALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL28295296 | 0.76 | NPC1 (0.48) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17343058 | 0.74 | TSHR (0.47) | LMNANPSR1ALDH1A1GAATP53 | |
| SCHEMBL7601325 | 0.74 | MAPT (0.53) | LMNAPOLBRAB9AALDH1A1TP53 | |
| SCHEMBL6331211 | 0.74 | KCNA5 (0.43) | CYP3A4CYP2C19POLBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264707-A2 | Thermosensitive recording material and novel color developer compounds | OJI PAPER CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |