Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PYGM | P11217 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601962 | 0.86 | MAPT (0.45) | MAPTL3MBTL1POLBLMNAADRA2C | |
| SCHEMBL7601156 | 0.84 | TDP1 (0.54) | MTNR1BMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL7598040 | 0.80 | MTNR1B (0.51) | MTNR1BL3MBTL1TDP1CA12CA1 | |
| SCHEMBL7602552 | 0.80 | MTNR1B (0.39) | PTGDR2MTNR1BMAPTPYGML3MBTL1 | |
| SCHEMBL7598300 | 0.79 | MTNR1B (0.48) | PTGDR2MTNR1BMAPTL3MBTL1POLB | |
| SCHEMBL7601427 | 0.77 | MTNR1B (0.40) | PTGDR2MTNR1BMAPTL3MBTL1POLB | |
| SCHEMBL7600768 | 0.76 | F10 (0.48) | PTGDR2MAPTPYGML3MBTL1LMNA | |
| SCHEMBL7601098 | 0.76 | TDP1 (0.48) | PTGDR2MTNR1BMAPTPYGML3MBTL1 | |
| SCHEMBL7602164 | 0.76 | MTNR1B (0.39) | PTGDR2MTNR1BPYGML3MBTL1POLB | |
| SCHEMBL8106747 | 0.75 | POLB (0.43) | PTGDR2MTNR1BMAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |