Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP12 | P39900 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP16 | P51512 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597944 | 0.89 | GAA (0.47) | GAAALDH1A1ADRA2CL3MBTL1POLB | |
| SCHEMBL7602651 | 0.83 | GAA (0.52) | GAAALDH1A1ADRA2CL3MBTL1POLB | |
| SCHEMBL7602530 | 0.83 | GAA (0.59) | GAAALDH1A1ADRA2CL3MBTL1POLB | |
| SCHEMBL7602716 | 0.82 | ALDH1A1 (0.53) | GAAALDH1A1ADRA2CL3MBTL1POLB | |
| SCHEMBL7601793 | 0.82 | ALDH1A1 (0.50) | GAAALDH1A1ADRA2CL3MBTL1SMN1; SMN2 | |
| SCHEMBL7601066 | 0.82 | ALDH1A1 (0.58) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7601089 | 0.81 | TDP1 (0.51) | ALDH1A1ADRA2CL3MBTL1MMP2MMP9 | |
| SCHEMBL7599812 | 0.80 | GAA (0.56) | GAAALDH1A1ADRA2CL3MBTL1POLB | |
| SCHEMBL7599804 | 0.80 | PRMT1 (0.59) | GAAALDH1A1MMP2MMP9MMP12 | |
| SCHEMBL7599801 | 0.78 | CA1 (0.43) | ALDH1A1POLBMMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |