Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.59 |
| ▸ | DBH | P09172 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660262 | 0.93 | ESR1 (0.52) | ESR1ESR2DBHPDE5ATP53 | |
| SCHEMBL7607371 | 0.90 | ESR1 (0.49) | ESR1ESR2DBHPDE5AC5AR1 | |
| SCHEMBL7603399 | 0.83 | ESR1 (0.49) | ESR1ESR2DBHPDE5AAR | |
| SCHEMBL21360607 | 0.78 | TRPA1 (0.47) | ESR1DBHTP53TDP1AR | |
| SCHEMBL4635049 | 0.78 | C5AR1 (0.44) | ESR1ESR2C5AR1KDM4EMEN1 | |
| SCHEMBL5155008 | 0.77 | ALDH1A1 (0.48) | TDP1KDM4ETHRATHRBMEN1 | |
| SCHEMBL27371273 | 0.75 | ESR1 (0.68) | ESR1ESR2DBHTP53TDP1 | |
| SCHEMBL36509 | 0.74 | ESR1 (1.00) | ESR1ESR2DBHTP53TDP1 | |
| SCHEMBL1924746 | 0.74 | ESR1 (0.74) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL29357262 | 0.74 | ESR1 (1.00) | ESR1ESR2DBHTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451888-B1 | Solid stabilizer composition with improved hydrolytic stability | GENERAL ELECTRIC COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6033600-A | PENTAERYTHRITOL PHOSPHITE, A HINDERED PHENOLIC ISOCYANURATE, A METAL SALT OF A FATTY ACID AND HYDROTALCITE. | GENERAL ELECTRIC COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0685516-B1 | Solid stabilizer composition with improved hydrolytic stability | GEN ELECTRIC (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0685516-A1 | Solid stabilizer composition with improved hydrolytic stability | GENERAL ELECTRIC COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5162406-A | Containing hydroxyphenylalkylenyl isocyanurate, polyphenylene diphosphonite and ackylidene bisphenol | THE DOW CHEMICAL COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-4923909-A | THIXOTROPIC SLURRYING; PIPES; STABILITY; THERMOPLASTIC OR THERMOSETTING RESIN; LIQUID CARRIER | THE B. F. GOODRICH COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4025486-A | PENTAERYTHRITOL PHOSPHITE COMBINATIONS AS ULTRAVIOLET LIGHT STABILIZERS FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1977-05-24 | — | — | US | disclosed |