Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
| ▸ | PRKACB | P22694 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598151 | 0.93 | ESR1 (0.59) | ESR1ESR2DBHPDE5AC5AR1 | |
| SCHEMBL7607371 | 0.84 | ESR1 (0.49) | ESR1ESR2DBHPDE5AC5AR1 | |
| SCHEMBL2305294 | 0.82 | ESR1 (0.48) | ESR1ESR2DBHPDE5A | |
| SCHEMBL7603399 | 0.78 | ESR1 (0.49) | ESR1ESR2DBHPDE5AKDM4E | |
| SCHEMBL11177663 | 0.74 | ESR1 (0.83) | ESR1ESR2BACE1KDM4EIDH1 | |
| SCHEMBL3241376 | 0.74 | ESR1 (0.63) | ESR1ESR2KDM4ETP53TDP1 | |
| SCHEMBL6234291 | 0.74 | ESR1 (0.83) | ESR1ESR2BACE1KDM4EIDH1 | |
| SCHEMBL22067844 | 0.74 | L3MBTL1 (0.47) | TP53MEN1KMT2A | |
| SCHEMBL21360607 | 0.72 | TRPA1 (0.47) | ESR1DBHBACE1KDM4ETP53 | |
| SCHEMBL4635049 | 0.72 | C5AR1 (0.44) | ESR1ESR2C5AR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710071-B1 | COLOURING COMPOSITION FOR THERMOPLASTIC POLYMERS AND PROCESS OF PREPARING AND USING SAME | TRADING AND MARKETING CONSULTANTS PALMAROLE AG (CH) | 2015-04-22 | — | — | EP | disclosed |