Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607371 | 0.88 | ESR1 (0.49) | ESR1ESR2DBHALDH1A1KMT2A | |
| SCHEMBL7598151 | 0.83 | ESR1 (0.59) | ESR1ESR2DBHKMT2AMEN1 | |
| SCHEMBL7631700 | 0.82 | MAOA (0.40) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL7601523 | 0.81 | THRB (0.42) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL16660262 | 0.78 | ESR1 (0.52) | ESR1ESR2DBHKMT2AMEN1 | |
| SCHEMBL7608593 | 0.76 | LMNA (0.46) | DBHALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL11721250 | 0.76 | P2RX4 (0.49) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL2337883 | 0.70 | HPGD (0.58) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL7601729 | 0.69 | KMT2A (0.43) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL456005 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451888-B1 | Solid stabilizer composition with improved hydrolytic stability | GENERAL ELECTRIC COMPANY | 2002-09-17 | — | — | US | disclosed |
| EP-0685516-B1 | Solid stabilizer composition with improved hydrolytic stability | GEN ELECTRIC (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0685516-A1 | Solid stabilizer composition with improved hydrolytic stability | GENERAL ELECTRIC COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5162406-A | Containing hydroxyphenylalkylenyl isocyanurate, polyphenylene diphosphonite and ackylidene bisphenol | THE DOW CHEMICAL COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-4923909-A | THIXOTROPIC SLURRYING; PIPES; STABILITY; THERMOPLASTIC OR THERMOSETTING RESIN; LIQUID CARRIER | THE B. F. GOODRICH COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0106169-B1 | SUBSTITUTED 2-(2,6-DI-T-BUTYL-4-ALKYLPHENOXY) 4H-1,3,2-BENZODIOXAPHOSPHORINS AND COMPOSITIONS THEREOF | The B.F. GOODRICH Company (US) | 1988-01-07 | — | — | EP | disclosed |
| EP-0128368-B1 | 2,4,6-TRIS(SUBSTITUTED PHENOXY)-1,3,5,2,4,6-TRIOXATRIPHOSPHORINANES | The B.F. GOODRICH Company (US) | 1987-08-12 | — | — | EP | disclosed |
| US-4584146-A | Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites | THE B. F. GOODRICH COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| US-4529533-A | Substituted 2-(2,6-di-t-butly-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| US-4522735-A | Polyphosphoramidite oligomers and stabilizer compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4495320-A | 3,6-Di-t-butyl-2-naphthyl catechol phosphite and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-01-22 | — | — | US | disclosed |
| EP-0128368-A1 | 2,4,6-Tris(substituted phenoxy)-1,3,5,2,4,6-trioxatriphosphorinanes | The B.F. GOODRICH Company (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4472548-A | HYDROXYPHENYLALKYL ISOCYANURATE, STABILIZERS | THE B. F. GOODRICH COMPANY (US) | 1984-09-18 | — | — | US | disclosed |
| EP-0110293-A2 | Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof | The B.F. GOODRICH Company (US) | 1984-06-13 | — | — | EP | disclosed |
| EP-0106169-A1 | Substituted 2-(2,6-di-t-butyl-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof | The B.F. GOODRICH Company (US) | 1984-04-25 | — | — | EP | disclosed |
| US-4444929-A | Unsymmetrical phosphite-phenolic isocyanurate stabilizer combinations | THE B. F. GOODRICH COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| EP-0104643-A2 | 5-Membered cyclic phosphonates and compositions thereof | The B.F. GOODRICH Company (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4439564-A | 5-Membered cyclic phosphonates and compositions thereof | THE B. F. GOODRICH CO. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4415686-A | Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1983-11-15 | — | — | US | disclosed |
| US-4025486-A | PENTAERYTHRITOL PHOSPHITE COMBINATIONS AS ULTRAVIOLET LIGHT STABILIZERS FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1977-05-24 | — | — | US | disclosed |