Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179217 | 1.00 | MEN1 (0.48) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6866131 | 0.82 | MEN1 (0.48) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6859753 | 0.82 | MEN1 (0.48) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11823698 | 0.69 | MEN1 (0.83) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8507346 | 0.67 | RAB9A (0.87) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL799431 | 0.67 | RAB9A (0.87) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8526512 | 0.67 | RAB9A (0.87) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL19994665 | 0.66 | MLYCD (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7088459 | 0.66 | ALOX5 (0.41) | KMT2AALDH1A1SMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL4814784 | 0.66 | MAPK1 (0.58) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087842-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |