Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598284 | 0.80 | GAA (0.50) | CA12CA1CA2CA9ATM | |
| SCHEMBL7599801 | 0.78 | CA1 (0.43) | CA12CA1CA2CA9MMP1 | |
| SCHEMBL7598919 | 0.76 | PRMT1 (0.56) | PRMT1CA12CA1CA2CA9 | |
| SCHEMBL7602615 | 0.75 | PRMT1 (0.67) | PRMT1CA12CA1CA2CA9 | |
| SCHEMBL7597396 | 0.74 | PRMT1 (0.64) | PRMT1CA12CA1CA2CA9 | |
| SCHEMBL7597944 | 0.73 | GAA (0.47) | ATMKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL11156936 | 0.72 | CA2 (0.50) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10919761 | 0.71 | KCNJ5 (0.67) | PRMT1CA12CA1CA2CA9 | |
| SCHEMBL6001655 | 0.70 | CA1 (0.57) | PRMT1CA12CA1CA2CA9 | |
| SCHEMBL4443824 | 0.70 | ALDH1A1 (0.40) | KMT2ACYP2C19MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |