Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | KLK7 | P49862 | 2/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597561 | 0.92 | ALOX5 (0.48) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL7594440 | 0.89 | TPSAB1 (0.45) | CTSSCTSKTPSAB1TPSD1TPSG1 | |
| SCHEMBL7594433 | 0.89 | TPSAB1 (0.45) | CTSSCTSKTPSAB1TPSD1TPSG1 | |
| SCHEMBL7598318 | 0.89 | TPSAB1 (0.45) | CTSSCTSKTPSAB1TPSD1TPSG1 | |
| SCHEMBL7597375 | 0.89 | MAPT (0.49) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL7595041 | 0.88 | MAPT (0.47) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL7594753 | 0.88 | MAPT (0.47) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7600343 | 0.88 | MAPT (0.48) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL7597577 | 0.88 | CTSS (0.46) | CTSSCTSKMAPTFOLH1ALOX5 | |
| SCHEMBL7597737 | 0.87 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |