Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598850 | 0.92 | ALOX5 (0.49) | FOLH1ALOX5MAPTL3MBTL1HTT | |
| SCHEMBL7600868 | 0.89 | FOLH1 (0.45) | CTSSCTSKFOLH1ALOX5MAPT | |
| SCHEMBL7595812 | 0.89 | FOLH1 (0.49) | FOLH1DPP8DPP7HTT | |
| SCHEMBL7597839 | 0.89 | FOLH1 (0.49) | FOLH1DPP8DPP7HTT | |
| SCHEMBL7597929 | 0.88 | CA1 (0.45) | CTSSCTSKFOLH1ALOX5MAPT | |
| SCHEMBL7600355 | 0.88 | CA1 (0.45) | CTSSCTSKFOLH1ALOX5MAPT | |
| SCHEMBL7596318 | 0.88 | GPR88 (0.44) | GPR88ACACA | |
| SCHEMBL7598409 | 0.88 | CTSS (0.45) | CTSSCTSKFOLH1ALOX5GPR88 | |
| SCHEMBL7597117 | 0.87 | FOLH1 (0.46) | FOLH1DPP8DPP7HTT | |
| SCHEMBL7595116 | 0.87 | FOLH1 (0.46) | FOLH1DPP8DPP7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |