Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887185 | 0.91 | — | — | |
| SCHEMBL7597026 | 0.87 | DHFR (0.30) | DHFR | |
| SCHEMBL7597611 | 0.84 | — | — | |
| SCHEMBL797329 | 0.83 | TLR8 (0.32) | DHFR | |
| SCHEMBL7602791 | 0.81 | HTR7 (0.36) | DHFR | |
| Hydrochloric Acid SCHEMBL3356796 | 0.80 | DHFR (0.35) | DHFR | |
| SCHEMBL7601455 | 0.80 | DHFR (0.32) | DHFR | |
| Hydrochloric Acid SCHEMBL969634 | 0.80 | DHFR (0.32) | DHFR | |
| Hydrochloric Acid SCHEMBL7586032 | 0.80 | DHFR (0.32) | DHFR | |
| SCHEMBL6890201 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |