Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599303 | 0.84 | HTR7 (0.36) | HTR7HTR1ACNR1CNR2CYP2D6 | |
| SCHEMBL796777 | 0.83 | HTR7 (0.36) | HTR7HTR1ACNR1CNR2DHFR | |
| SCHEMBL7598615 | 0.81 | DHFR (0.32) | DHFR | |
| SCHEMBL7601455 | 0.81 | DHFR (0.32) | DHFRSLC6A4SLC6A2SLC6A3MAPT | |
| Hydrochloric Acid SCHEMBL5616484 | 0.80 | HTR7 (0.36) | HTR7HTR1ACNR1CNR2BRD4 | |
| Hydrochloric Acid SCHEMBL218908 | 0.80 | HTR7 (0.36) | HTR7HTR1ACNR1CNR2BRD4 | |
| Hydrochloric Acid SCHEMBL218124 | 0.80 | HTR7 (0.36) | HTR7HTR1ACNR1CNR2BRD4 | |
| SCHEMBL7602061 | 0.80 | HTR7 (0.39) | HTR7HTR1ACNR1CNR2BRD4 | |
| SCHEMBL7597026 | 0.78 | DHFR (0.30) | DHFR | |
| SCHEMBL796673 | 0.73 | HTR7 (0.36) | HTR7HTR1ACNR1CNR2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |