SCHEMBL7599227

SCHEMBL7599227

CCCCCN1C(=O)C2=C(CCCC2)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.47
FAAH O00519 4/20 0.47
PTGS1 P23219 3/20 0.47
PTGS2 P35354 3/20 0.47
ALOX5 P09917 2/20 0.42
ALDH1A1 P00352 2/20 0.41
ALDH2 P05091 1/20 0.41
ALDH3A1 P30838 1/20 0.41
CES1 P23141 2/20 0.40
CDC25A P30304 1/20 0.40
HTR7 P34969 1/20 0.40
LMNA P02545 3/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
NPC1 O15118 2/20 0.37
SLC2A1 P11166 2/20 0.37
RAB9A P51151 2/20 0.37
PAX8 Q06710 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10908051 0.87 HTR7 (0.43) MGLLFAAHALDH1A1HTR7LMNA
SCHEMBL7153652 0.80 MGLL (0.60) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL11794337 0.80 MGLL (0.41) MGLLFAAHPTGS1PTGS2ALOX5
SCHEMBL7749309 0.78 MGLL (0.59) MGLLFAAHPTGS1PTGS2ALOX5
SCHEMBL7743712 0.78 MGLL (0.59) MGLLFAAHPTGS1PTGS2ALOX5
SCHEMBL14359201 0.78 KDM4E (0.40) ALDH1A1HTR7LMNAKDM4EMAPT
SCHEMBL7263257 0.77 HTR7 (0.39) MGLLFAAHALDH1A1HTR7LMNA
SCHEMBL10031631 0.76 LMNA (0.44) MGLLALDH1A1LMNAKDM4EMAPT
SCHEMBL718406 0.75 MGLL (0.61) MGLLFAAHPTGS1PTGS2ALOX5
SCHEMBL15998794 0.74 KDM4E (0.38) MGLLALDH1A1HTR7LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0923286-B1 LIQUID FORMULATION OF ETHYL-(Z)-2-CHLORO-3-2-CHLORO-5-(4,5,6,7-TETRAHYDRO-1,3-DIOXOISOINDOLDION-2-YL)PHENYLACRYLATE BASF AG (DE) 2002-10-30 EP disclosed
US-6225259-B1 IONIC EMULSIFIER, NON-IONIC EMULSIFIER, NON-NUCLEOPHILIC AND NON-BASIC AROMATIC SOLVENT BASF AKTIENGESELLSCHAFT (DE) 2001-05-01 US disclosed
EP-0923286-A1 LIQUID FORMULATION OF ETHYL-(Z)-2-CHLORO-3-2-CHLORO-5-(4,5,6,7-TETRAHYDRO-1,3-DIOXOISOINDOLDION-2-YL)PHENYLACRYLATE BASF AKTIENGESELLSCHAFT (DE) 1999-06-23 EP disclosed
WO-1998007319-A1 LIQUID FORMULATION OF ETHYL-(Z)-2-CHLORO-3-2-CHLORO-5-(4,5,6,7-TETRAHYDRO-1,3-DIOXOISOINDOLDION-2-YL)PHENYLACRYLATE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 WO disclosed
US-H531-H BROAD LEAF PLANTS RHONE POULENC NEDERLANDS B.V. (NL) 1988-10-04 US disclosed
WO-1987007602-A2 N-(5-SUBSTITUTED METHYLENE) PHENYL HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1987-12-17 WO disclosed
EP-0216243-A2 N-substituted 3,4,5,6-tetrahydrophthalimide, process for their preparation and their use as herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-01 EP disclosed
US-4536209-A N-(3-substituted oxyphenyl)tetrahydrophthalimides and herbicidal composition MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1985-08-20 US disclosed
US-4420327-A Tetrahydrophthalimides and herbicidal composition MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1983-12-13 US disclosed
EP-0077938-A2 N-(3-substituted aminophenyl) tetrahydrophthalimides and herbicidal composition MITSUBISHI KASEI CORPORATION (JP) 1983-05-04 EP disclosed
EP-0049511-A1 Tetrahydrophthalimides and herbicidal composition MITSUBISHI KASEI CORPORATION (JP) 1982-04-14 EP disclosed
EP-0049508-A1 N-(3-Substituted oxyphenyl) tetrahydrophthalimides and herbicidal composition MITSUBISHI KASEI CORPORATION (JP) 1982-04-14 EP disclosed
US-4292070-A N-Substituted tetrahydrophthalimide and herbicidal composition MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1981-09-29 US disclosed
US-4032326-A HERBICIDAL 2-SUBSTITUTED ARYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-28 US disclosed
US-4032326-A HERBICIDAL 2-SUBSTITUTED ARYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-28 US disclosed
US-3992189-A Herbicidal isoindol-1-one derivatives E. I. DU PONT DE NEMOURS & COMPANY (US) 1976-11-16 US disclosed