Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908051 | 0.85 | HTR7 (0.43) | KDM4ELMNAHTR7KMT2AALDH1A1 | |
| SCHEMBL7599227 | 0.78 | MGLL (0.47) | KDM4ELMNAHTR7KMT2AALDH1A1 | |
| SCHEMBL15998794 | 0.76 | KDM4E (0.38) | KDM4ELMNAHTR7KMT2AALDH1A1 | |
| SCHEMBL7263257 | 0.75 | HTR7 (0.39) | KDM4ELMNAHTR7ALDH1A1L3MBTL1 | |
| SCHEMBL7802057 | 0.75 | MEN1 (0.47) | KDM4ELMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL21389153 | 0.74 | KDM4E (0.42) | KDM4ELMNAHTR7USP2NPSR1 | |
| SCHEMBL10262842 | 0.74 | KDM4E (0.42) | KDM4ELMNAHTR7KMT2AALDH1A1 | |
| SCHEMBL6273408 | 0.74 | MEN1 (0.55) | HTR7KMT2AMEN1POLB | |
| SCHEMBL6866079 | 0.73 | MEN1 (0.44) | LMNAHTR7KMT2AALDH1A1MEN1 | |
| SCHEMBL3001679 | 0.71 | ALDH1A1 (0.40) | KDM4ELMNAHTR7KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013001498-A1 | AMIDOALKYLPIPERAZINYL DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | ADAMED SP. Z O.O. (PL) | 2013-01-03 | — | — | WO | disclosed |