Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971729 | 0.81 | QRFPR (0.47) | QRFPRLMNAMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7598799 | 0.80 | QRFPR (0.46) | QRFPRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL7599390 | 0.74 | QRFPR (0.59) | QRFPR | |
| SCHEMBL7599901 | 0.73 | QRFPR (0.46) | QRFPRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL7600936 | 0.71 | QRFPR (0.48) | QRFPRLMNAMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7598592 | 0.70 | QRFPR (0.47) | QRFPRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL7598787 | 0.70 | KMT2A (0.39) | QRFPRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL7597196 | 0.69 | ATM (0.39) | QRFPRLMNAMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7599078 | 0.69 | ATM (0.38) | QRFPRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL7602422 | 0.69 | QRFPR (0.36) | QRFPRLMNAMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137750-A1 | Amidine derivatives which are inhibitors of nitric oxide synthase | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | US | claimed |
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | claimed |
| EP-0877251-B1 | Dry analytical elements for the determination of protein | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2002-11-27 | — | — | EP | disclosed |
| US-20020137750-A1 | Amidine derivatives which are inhibitors of nitric oxide synthase | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | US | disclosed |
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |
| US-6046052-A | FOR SENSITIVE, ACCURATE AND RAPID DETECTION AND QUANTITATION; INCLUDES A POROUS SPREADING LAYER AND ONE OR MORE LAYERS OF INDICATOR DYE, MOLYBDATE SALT, AN ACRYLAMIDE POLYMER TO STABILIZE THE ASSAY AND A SUPPORT | ORTHO CLINICAL DIAGNOSTICS, INC. (US) | 2000-04-04 | — | — | US | disclosed |
| EP-0952451-A1 | Dry analytical elements for the determination of protein | Ortho-Clinical Diagnostics, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| EP-0877251-A1 | Dry analytical elements for the determination of protein | Ortho-Clinical Diagnostics, Inc. (US) | 1998-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137750-A1 | Amidine derivatives which are inhibitors of nitric oxide synthase | NOS1, NOS2, NOS3 | QRFPR 1455/4885LMNA 1976/4885PDCD1 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.