Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097649 | 0.90 | LMNA (0.39) | LMNAALDH1A1MAPTHTTPKM | |
| SCHEMBL7602164 | 0.86 | MTNR1B (0.39) | MTNR1BPTGDR2NAMPTLMNAALDH1A1 | |
| SCHEMBL7598300 | 0.84 | MTNR1B (0.48) | MTNR1BPTGDR2LMNAALDH1A1MAPT | |
| SCHEMBL7602552 | 0.82 | MTNR1B (0.39) | MTNR1BPTGDR2LMNAALDH1A1MAPT | |
| SCHEMBL8106747 | 0.78 | POLB (0.43) | MTNR1BPTGDR2LMNAALDH1A1MAPT | |
| SCHEMBL7602516 | 0.78 | L3MBTL1 (0.37) | MTNR1BPTGDR2LMNAALDH1A1L3MBTL1 | |
| SCHEMBL7599476 | 0.77 | PTGDR2 (0.46) | MTNR1BPTGDR2LMNAALDH1A1MAPT | |
| SCHEMBL7598974 | 0.77 | KMT2A (0.41) | LMNAALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL7601939 | 0.77 | TDP1 (0.38) | MTNR1BPTGDR2LMNAALDH1A1MAPT | |
| SCHEMBL7601352 | 0.76 | KMT2A (0.41) | LMNAALDH1A1MAPTPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |