Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.47 |
| ▸ | THRA | P10827 | 7/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864242 | 0.79 | THRB (0.49) | THRBTHRAOPRK1 | |
| SCHEMBL7114452 | 0.79 | THRB (0.50) | THRBTHRA | |
| SCHEMBL282445 | 0.77 | THRB (0.49) | THRBTHRAOPRK1 | |
| SCHEMBL666032 | 0.77 | THRB (0.43) | THRBTHRAOPRK1 | |
| SCHEMBL6864460 | 0.77 | THRB (0.48) | THRBTHRAOPRK1 | |
| SCHEMBL6863331 | 0.76 | THRB (0.66) | THRBTHRA | |
| SCHEMBL6863345 | 0.73 | THRB (0.44) | THRBTHRAOPRK1 | |
| SCHEMBL667473 | 0.72 | THRB (0.45) | THRBTHRAOPRK1 | |
| SCHEMBL7590192 | 0.71 | ALDH1A1 (0.43) | THRBTHRA | |
| SCHEMBL667776 | 0.71 | THRB (0.39) | THRBTHRAOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194422-A1 | BIARYL COMPOUNDS | UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000073292-A1 | BIARYL COMPOUNDS | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2000-12-07 | — | — | WO | disclosed |