Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 17/20 | 0.52 |
| ▸ | MMP2 | P08253 | 15/20 | 0.52 |
| ▸ | MMP1 | P03956 | 8/20 | 0.52 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600044 | 1.00 | MMP9 (0.52) | MMP9MMP2MMP1MMP14CXCR4 | |
| SCHEMBL7599808 | 0.78 | MMP9 (0.55) | MMP9MMP2MMP1MMP14MMP3 | |
| SCHEMBL7603274 | 0.77 | MMP9 (0.47) | MMP9MMP2MMP1MMP14MMP3 | |
| SCHEMBL7600749 | 0.75 | MMP9 (0.43) | MMP9MMP2MMP1MMP14MMP3 | |
| SCHEMBL7435170 | 0.71 | MMP9 (0.64) | MMP9MMP2MMP1MMP14MMP3 | |
| SCHEMBL7598896 | 0.71 | MMP9 (0.64) | MMP9MMP2MMP1MMP14MMP3 | |
| SCHEMBL7435168 | 0.68 | MMP9 (1.00) | MMP9MMP2MMP1MMP3MMP8 | |
| SCHEMBL7598893 | 0.68 | MMP9 (1.00) | MMP9MMP2MMP1MMP3MMP8 | |
| SCHEMBL8005756 | 0.65 | MMP2 (0.50) | MMP9MMP2MMP1MMP14MMP3 | |
| SCHEMBL4696395 | 0.65 | MMP9 (0.43) | MMP9MMP2MMP1MMP14MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-B1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2002-11-20 | — | — | EP | claimed |