Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 18/20 | 0.43 |
| ▸ | MMP2 | P08253 | 12/20 | 0.43 |
| ▸ | MMP14 | P50281 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 7/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.39 |
| ▸ | MMP7 | P09237 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603274 | 0.79 | MMP9 (0.47) | MMP9MMP2MMP14MMP3MMP13 | |
| SCHEMBL7599808 | 0.79 | MMP9 (0.55) | MMP9MMP2MMP14MMP3MMP13 | |
| SCHEMBL7600044 | 0.75 | MMP9 (0.52) | MMP9MMP2MMP14MMP3MMP13 | |
| SCHEMBL7599651 | 0.75 | MMP9 (0.52) | MMP9MMP2MMP14MMP3MMP13 | |
| SCHEMBL7583731 | 0.74 | MMP9 (0.45) | MMP9MMP2MMP14MMP3MMP13 | |
| SCHEMBL7583727 | 0.70 | MMP9 (0.65) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL7583739 | 0.70 | MMP9 (0.65) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL8005756 | 0.65 | MMP2 (0.50) | MMP9MMP2MMP14MMP3MMP13 | |
| SCHEMBL7679710 | 0.64 | MMP9 (0.58) | MMP9MMP2MMP14MMP3MMP13 | |
| SCHEMBL7365907 | 0.63 | MMP2 (0.48) | MMP9MMP2MMP14MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-B1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2002-11-20 | — | — | EP | claimed |