SCHEMBL7599798

SCHEMBL7599798

CCCOC(=O)c1cccc(NC(=O)NS(=O)(=O)c2cccc(Cl)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 10/20 0.58
ALDH1A1 P00352 2/20 0.55
PFKFB3 Q16875 1/20 0.53
PFKFB4 Q16877 1/20 0.53
TRPV1 Q8NER1 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.48
LMNA P02545 3/20 0.48
PTBP1 P26599 1/20 0.48
HPGD P15428 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6721144 0.91 FBP1 (0.59) FBP1ALDH1A1TRPV1SMN1; SMN2HPGD
SCHEMBL6331862 0.91 ALDH1A1 (0.56) ALDH1A1PFKFB3PFKFB4TRPV1SMN1; SMN2
SCHEMBL6322969 0.89 ALDH1A1 (0.59) ALDH1A1PFKFB3PFKFB4SMN1; SMN2LMNA
SCHEMBL6324631 0.88 ALDH1A1 (0.56) FBP1ALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL6321973 0.85 LMNA (0.57) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL6322963 0.84 SMN1; SMN2 (0.55) ALDH1A1PFKFB3PFKFB4SMN1; SMN2LMNA
SCHEMBL6325357 0.82 SMN1; SMN2 (0.58) FBP1ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL6428589 0.82 FBP1 (0.59) FBP1ALDH1A1SMN1; SMN2LMNAPTBP1
SCHEMBL6326485 0.81 MEN1 (0.54) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL6324642 0.81 MEN1 (0.54) ALDH1A1SMN1; SMN2LMNAHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed