SCHEMBL6721144

SCHEMBL6721144

CCCOC(=O)c1ccc(NC(=O)NS(=O)(=O)c2cccc(Cl)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 11/20 0.59
TRPV1 Q8NER1 1/20 0.57
ALDH1A1 P00352 4/20 0.52
HPGD P15428 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.49
POLB P06746 1/20 0.48
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
THRB P10828 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7599798 0.91 FBP1 (0.58) FBP1TRPV1ALDH1A1HPGDSMN1; SMN2
SCHEMBL6731776 0.88 FBP1 (0.54) FBP1HPGDPOLBMEN1MAPT
SCHEMBL6720823 0.87 ALDH1A1 (0.53) TRPV1ALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL6725193 0.87 ALDH1A1 (0.59) ALDH1A1HPGDSMN1; SMN2POLBMEN1
SCHEMBL6724922 0.82 POLB (0.58) FBP1ALDH1A1HPGDSMN1; SMN2POLB
SCHEMBL7602192 0.82 FBP1 (0.60) FBP1ALDH1A1SMN1; SMN2THRBKMT2A
SCHEMBL6325376 0.81 CA2 (0.60) ALDH1A1HPGDSMN1; SMN2MEN1MAPT
SCHEMBL6331862 0.81 ALDH1A1 (0.56) TRPV1ALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL6725015 0.81 FBP1 (0.55) FBP1ALDH1A1HPGDPOLBMAPT
SCHEMBL6732314 0.81 HPGD (0.57) ALDH1A1HPGDSMN1; SMN2POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1044824-B1 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO (JP) 2004-05-12 EP disclosed
US-6677472-B2 AS COLOR-DEVELOPING AGENT; HIGH WHITENESS AND RESISTANCE TO COLOR FORMATION UNDER HIGH TEMPERATURE OJI PAPER CO., LTD. (JP) 2004-01-13 US disclosed
US-6486094-B1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-11-26 US disclosed
US-20020065196-A1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-05-30 US disclosed
EP-1044824-A2 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER COMPANY LIMITED (JP) 2000-10-18 EP disclosed