Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15166821 | 0.76 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CA12CYP3A4ATM | |
| P-Toluenesulfonamide SCHEMBL4747609 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CA12CA9CA2CA7 | |
| SCHEMBL6966789 | 0.74 | ALDH1A1 (0.49) | ALDH1A1CNR2CYP1A2BCHEACHE | |
| SCHEMBL6914203 | 0.73 | NPY2R (0.50) | ALDH1A1CYP1A2BCHEACHECA12 | |
| SCHEMBL28023019 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1CYP1A2ATMCYP2C9CYP2C19 | |
| SCHEMBL28664196 | 0.73 | ALDH1A1 (0.58) | ALDH1A1CNR2CYP1A2BCHEACHE | |
| SCHEMBL15242550 | 0.73 | ALDH1A1 (0.51) | ALDH1A1CNR2CYP1A2CA12CYP3A4 | |
| SCHEMBL10420695 | 0.73 | MMP2 (0.55) | ALDH1A1CNR2TP53MMP1MMP2 | |
| SCHEMBL4596569 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CNR2CYP1A2BCHEACHE | |
| SCHEMBL10420884 | 0.72 | MMP2 (0.54) | ALDH1A1CNR2TP53MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550506-B1 | NOVEL CHEMOTACTIC FACTOR | HEART RES INST LTD (AU) | 2002-11-20 | — | — | EP | disclosed |
| EP-0361284-B1 | T cell growth factor | LUDWIG INST CANCER RES (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5750377-A | SYNERGISTIC WITH INTERLEUKINS | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | disclosed |
| US-5731166-A | Recombinant production of chemotactic CP-10 polypeptides and therapeutic methods using them | THE HEART RESEARCH INSTITUTE LTD. (AU) | 1998-03-24 | — | — | US | disclosed |
| US-5587302-A | ISOLATED POLYNUCLEOTIDES ENCODES POLYPEPTIDE INTERLEUKINS | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1996-12-24 | — | — | US | disclosed |
| EP-0550506-A4 | NOVEL CHEMOTACTIC FACTOR | HEART RES INST (AU) | 1994-06-08 | — | — | EP | disclosed |
| EP-0550506-A1 | NOVEL CHEMOTACTIC FACTOR | THE HEART RESEARCH INSTITUTE LIMITED (AU) | 1993-07-14 | — | — | EP | disclosed |
| EP-0466854-A4 | T CELL GROWTH FACTOR | — | 1993-03-31 | — | — | EP | disclosed |
| US-5157112-A | Supports interleukin-2 and interleukin-4 independent growth of helper T cells | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 1992-10-20 | — | — | US | disclosed |
| WO-1992004376-A1 | NOVEL CHEMOTACTIC FACTOR | THE HEART RESEARCH INSTITUTE LIMITED (AU) | 1992-03-19 | — | — | WO | disclosed |
| EP-0466854-A1 | T CELL GROWTH FACTOR | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1992-01-22 | — | — | EP | disclosed |
| WO-1991010738-A1 | T CELL GROWTH FACTOR | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-07-25 | — | — | WO | disclosed |
| EP-0361284-A2 | T cell growth factor | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1990-04-04 | — | — | EP | disclosed |