SCHEMBL28023019

SCHEMBL28023019

CCCC(Cl)S(=O)(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
PSIP1 O75475 1/20 0.47
MMP1 P03956 4/20 0.44
MMP13 P45452 4/20 0.44
MMP7 P09237 3/20 0.44
MMP12 P39900 3/20 0.44
ACE P12821 2/20 0.44
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
HTR6 P50406 1/20 0.38
HSD11B1 P28845 1/20 0.38
PSEN1 P49768 1/20 0.37
PSEN2 P49810 1/20 0.37
APH1B Q8WW43 1/20 0.37
NCSTN Q92542 1/20 0.37
APH1A Q96BI3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3701827 0.84 PSIP1 (0.50) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL10768155 0.83 MMP2 (0.56) SMN1; SMN2MMP1MMP13MMP2MMP9
SCHEMBL28820920 0.80 MMP1 (0.54) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL12370397 0.78 SMN1; SMN2 (0.56) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL28604397 0.77 SMN1; SMN2 (0.50) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL3917298 0.77 SMN1; SMN2 (0.50) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL2448076 0.77 MMP1 (0.51) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL11566604 0.77 SMN1; SMN2 (0.50) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL28023657 0.77 SMN1; SMN2 (0.50) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL16690471 0.76 MMP13 (0.55) SMN1; SMN2PSIP1MMP1MMP13MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103509135-B Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2015-07-22 CN disclosed