Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967059 | 0.93 | JAK2 (0.33) | JAK2ABL1SRCRXFP1LCK | |
| SCHEMBL7480849 | 0.91 | AVPR2 (0.35) | AVPR2AVPR1AAVPR1BMAP3K7LMNA | |
| SCHEMBL7978293 | 0.90 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BLCKMAP3K7 | |
| Hydrochloric Acid SCHEMBL7481449 | 0.90 | AVPR2 (0.35) | AVPR2AVPR1AAVPR1BMAP3K7LMNA | |
| SCHEMBL7963915 | 0.90 | PTK2 (0.35) | AVPR2AVPR1AAVPR1BMAP3K7HTR4 | |
| Hydrochloric Acid SCHEMBL7963628 | 0.90 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BLCKMAP3K7 | |
| SCHEMBL7965069 | 0.90 | LMNA (0.36) | AVPR2AVPR1AAVPR1BMAP3K7LMNA | |
| Dimethylamine SCHEMBL7972125 | 0.90 | AVPR2 (0.35) | AVPR2AVPR1AAVPR1BMAP3K7LMNA | |
| SCHEMBL7964762 | 0.90 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7LMNA | |
| Hydrochloric Acid SCHEMBL7970318 | 0.89 | PTK2 (0.34) | AVPR2AVPR1AAVPR1BMAP3K7HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |