Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394047 | 0.92 | NAMPT (0.49) | CCKBRPDCD1CD274NAMPTITGB3 | |
| SCHEMBL7397295 | 0.82 | RAB9A (0.39) | CCKBRNAMPTITGB3ITGA2BITGB1 | |
| SCHEMBL8195620 | 0.80 | ITGB3 (0.49) | CCKBRNAMPTITGB3ITGA2BITGB1 | |
| SCHEMBL7600109 | 0.77 | ITGB3 (0.65) | CCKBRNAMPTBRD4CREBBPITGB3 | |
| SCHEMBL7600102 | 0.77 | ITGB3 (0.65) | CCKBRNAMPTBRD4CREBBPITGB3 | |
| SCHEMBL7397343 | 0.75 | ITGB3 (0.43) | NAMPTITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7400352 | 0.72 | NAMPT (0.55) | CCKBRNAMPTNPY1RITGB3ITGA2B | |
| SCHEMBL7391455 | 0.71 | ITGB3 (0.42) | BRD4ITGB3ITGA2BALDH1A1TSHR | |
| SCHEMBL8519376 | 0.71 | CCKBR (0.39) | CCKBRPDCD1CD274NAMPTBRD4 | |
| SCHEMBL7595536 | 0.71 | ITGB3 (0.70) | NAMPTITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |