Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600543 | 0.80 | MTTP (0.42) | MTTPPDK2 | |
| SCHEMBL6771005 | 0.79 | MTTP (0.50) | MTTP | |
| SCHEMBL7600948 | 0.78 | MTTP (0.43) | MTTPPDK2 | |
| SCHEMBL6651297 | 0.77 | THRB (0.41) | — | |
| SCHEMBL7595701 | 0.76 | PGR (0.36) | — | |
| SCHEMBL7603311 | 0.71 | MTTP (0.44) | MTTP | |
| SCHEMBL19335203 | 0.69 | MAPT (0.34) | — | |
| SCHEMBL7596692 | 0.69 | MTTP (0.36) | MTTPPDK2 | |
| SCHEMBL7611938 | 0.69 | SIGMAR1 (0.46) | — | |
| SCHEMBL8895346 | 0.68 | MTTP (0.52) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255736-A2 | SUBSTITUTED PIPERAZINE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) | Boehringer Ingelheim Pharma KG (DE) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001047898-A2 | SUBSTITUTED PIPERAZINE DERIVATIVES AND THEIR USE AS INHIBITORS OF THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |