Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775211 | 0.72 | EEF2K (0.32) | EEF2K | |
| Hydrochloric Acid SCHEMBL717823 | 0.71 | SIGMAR1 (0.31) | — | |
| SCHEMBL7600223 | 0.68 | DRD2 (0.31) | EEF2K | |
| SCHEMBL8057462 | 0.64 | SIGMAR1 (0.32) | — | |
| SCHEMBL4117096 | 0.55 | TRPV1 (0.41) | EEF2K | |
| SCHEMBL21971406 | 0.55 | GAA (0.47) | EEF2K | |
| SCHEMBL24775784 | 0.55 | GAA (0.39) | EEF2K | |
| SCHEMBL24774527 | 0.55 | CHRNA7 (0.37) | EEF2K | |
| SCHEMBL26219177 | 0.54 | MAPK1 (0.70) | — | |
| SCHEMBL23064483 | 0.54 | KEAP1 (0.48) | EEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124834-B1 | PREPARATION OF TITANIUM(II) OR ZIRCONIUM(II) COMPLEXES | DOW CHEMICAL CO (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6090962-A | Preparation of titanium(II) or zirconium(II) complexes | THE DOW CHEMICAL COMPANY (US) | 2000-07-18 | — | — | US | disclosed |