Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6889130 | 0.85 | SYK (0.33) | SYKEDNRBEDNRAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27495381 | 0.84 | PDCD1 (0.33) | EDNRBEDNRAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7934283 | 0.84 | MAOA (0.32) | AURKBALDH1A1 | |
| Hydrochloric Acid SCHEMBL29424591 | 0.83 | PDCD1 (0.35) | ALDH1A1HPGDHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL3163965 | 0.83 | PDCD1 (0.35) | ALDH1A1HPGDHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL5709184 | 0.83 | PDCD1 (0.35) | ALDH1A1HPGDHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL27513156 | 0.82 | HTR2C (0.35) | ABL1CLK4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL27513161 | 0.82 | NPC1 (0.35) | EDNRBEDNRAHPGDHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7601759 | 0.82 | ABL1 (0.38) | ABL1ABCB1BCRSYKAURKB | |
| Hydrochloric Acid SCHEMBL29612302 | 0.82 | ABL1 (0.40) | ABL1ABCB1BCRNR1H4SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263847-A1 | PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER | Borealis Technology Oy (FI) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062832-A1 | PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER | BOREALIS TECHNOLOGY OY (FI) | 2001-08-30 | — | — | WO | disclosed |
| EP-1123319-A2 | SUPPORTED POLYMERIZATION CATALYSTS | Borealis Technology (FI) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000022011-A2 | SUPPORTED POLYMERIZATION CATALYSTS | BOREALIS TECHNOLOGY OY (FI) | 2000-04-20 | — | — | WO | disclosed |