Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903507 | 0.79 | KMT2A (0.40) | ALDH1A1KMT2AGAAPOLBMEN1 | |
| SCHEMBL6905915 | 0.79 | KMT2A (0.40) | ALDH1A1KMT2AGAAPOLBMEN1 | |
| SCHEMBL6907956 | 0.79 | KMT2A (0.40) | ALDH1A1KMT2AGAAPOLBMEN1 | |
| SCHEMBL7639019 | 0.78 | POLB (0.41) | ALDH1A1KMT2AGAAPOLBMEN1 | |
| SCHEMBL7716682 | 0.72 | KMT2A (0.39) | ALDH1A1KDM4EKMT2AGAAPOLB | |
| SCHEMBL7610955 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KMT2AGAAPOLBHPGD | |
| SCHEMBL2117154 | 0.71 | KMT2A (0.53) | ALDH1A1KDM4EKMT2AGAAPOLB | |
| SCHEMBL4981052 | 0.70 | KMT2A (0.40) | ALDH1A1KDM4EKMT2AGAAPOLB | |
| SCHEMBL2119946 | 0.70 | KMT2A (0.56) | ALDH1A1KDM4EKMT2AGAAPOLB | |
| SCHEMBL28847733 | 0.69 | HPGD (0.47) | ALDH1A1KDM4EKMT2AGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384265-B1 | ACID CATALYSIS FOR REARRANGEMENT/INVERSION OF STEREOCONFIGURATION; KINETIC RESOLUTION OF RACEMIC MIXTURES USING A CHIRAL CATALYST | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION | 2002-05-07 | — | — | US | disclosed |
| EP-1169291-A1 | METHODS FOR PRODUCING $g(a)-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000056696-A1 | METHODS FOR PRODUCING α-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-09-28 | — | — | WO | disclosed |