Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597793 | 1.00 | POLB (0.41) | POLBGAAMAPK1NPSR1LMNA | |
| SCHEMBL6903507 | 0.99 | KMT2A (0.40) | POLBGAAMAPK1NPSR1LMNA | |
| SCHEMBL6905915 | 0.99 | KMT2A (0.40) | POLBGAAMAPK1NPSR1LMNA | |
| SCHEMBL6907956 | 0.99 | KMT2A (0.40) | POLBGAAMAPK1NPSR1LMNA | |
| SCHEMBL7596827 | 0.94 | LMNA (0.39) | POLBGAAMAPK1NPSR1LMNA | |
| SCHEMBL7588385 | 0.86 | ALDH1A1 (0.40) | GAANPSR1LMNACYP2D6KMT2A | |
| SCHEMBL7610955 | 0.84 | ALDH1A1 (0.41) | POLBGAACYP1A2SCN1ASCN2A | |
| SCHEMBL7597565 | 0.83 | SMN1; SMN2 (0.45) | POLBNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7630204 | 0.80 | PTPN2 (0.44) | POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL7597063 | 0.79 | MEN1 (0.38) | POLBNPSR1LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384265-B1 | ACID CATALYSIS FOR REARRANGEMENT/INVERSION OF STEREOCONFIGURATION; KINETIC RESOLUTION OF RACEMIC MIXTURES USING A CHIRAL CATALYST | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION | 2002-05-07 | — | — | US | disclosed |