SCHEMBL760108

SCHEMBL760108

CCCCn1nc(C(F)(F)F)cc1S(C)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
PTGS2 P35354 9/20 0.39
PTGS1 P23219 2/20 0.39
PDPK1 O15530 2/20 0.38
CNR1 P21554 3/20 0.36
CNR2 P34972 3/20 0.36
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20381740 0.78 CNR1 (0.47) LMNAPDPK1CNR1CNR2
SCHEMBL757069 0.77 RAB9A (0.47) LMNAPTGS2PTGS1CYP2C9ALDH1A1
SCHEMBL27507519 0.76 LMNA (0.43) LMNACNR1CNR2
SCHEMBL27667658 0.76 LMNA (0.40) LMNAPDPK1CNR1CNR2
SCHEMBL27783208 0.76 LMNA (0.40) LMNAPDPK1CNR1CNR2
SCHEMBL16592099 0.75 LMNA (0.39) LMNAPDPK1CNR1CNR2
SCHEMBL28943994 0.75 CNR1 (0.50) LMNACNR1CNR2
SCHEMBL758413 0.74 LMNA (0.38) LMNAPDPK1CNR1CNR2ALDH1A1
SCHEMBL27727992 0.74 CNR2 (0.49) LMNACNR1CNR2ALDH1A1CYP3A4
SCHEMBL27761426 0.73 LMNA (0.37) LMNAPDPK1CNR1CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101511818-B N-pyridylpiperidine compound, method for producing the same, and pest control agent OTSUKA AGRITECHNO CO LTD 2013-05-08 CN disclosed
EP-2050745-B1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA AGRITECHNO CO LTD (JP) 2012-03-21 EP disclosed
US-7994094-B2 N-pyridylpiperidine compound, method for producing the same, and pest control agent OTSUKA AGRITECHNO CO., LTD. (JP) 2011-08-09 US disclosed
US-7994094-B2 N-pyridylpiperidine compound, method for producing the same, and pest control agent OTSUKA AGRITECHNO CO., LTD. (JP) 2011-08-09 US disclosed
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA CHEMICAL CO., LTD. (JP) 2010-06-03 US disclosed
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA CHEMICAL CO., LTD. (JP) 2010-06-03 US disclosed
CN-101511818-A N-pyridylpiperidine compound, method for producing the same, and pest control agent OTSUKA CHEMICAL CO LTD (JP) 2009-08-19 CN disclosed
EP-2050745-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Otsuka Chemical Co., Ltd. (JP) 2009-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT HRH4, NOX4, PRDX4 LMNA 4100/4885PTGS2 3531/4885PTGS1 3229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.