Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517331 | 0.90 | MEN1 (0.52) | MEN1KMT2AHRH3POLBALDH1A1 | |
| SCHEMBL7601254 | 0.87 | POLB (0.55) | MEN1KMT2AHRH3POLBALDH1A1 | |
| SCHEMBL516950 | 0.84 | MEN1 (0.54) | MEN1KMT2AHRH3POLBALDH1A1 | |
| SCHEMBL16457383 | 0.84 | MEN1 (0.54) | MEN1KMT2AHRH3POLBALDH1A1 | |
| SCHEMBL10227019 | 0.79 | MEN1 (0.43) | MEN1KMT2AHRH3POLBALDH1A1 | |
| SCHEMBL7898855 | 0.79 | MEN1 (0.43) | MEN1KMT2AHRH3ALDH1A1KDM4E | |
| SCHEMBL1177794 | 0.78 | PTGES (0.52) | — | |
| SCHEMBL10176605 | 0.78 | MEN1 (0.42) | MEN1KMT2AHRH3POLBALDH1A1 | |
| SCHEMBL1177974 | 0.77 | MET (0.42) | MEN1KMT2AHRH3KDM4ECNR1 | |
| SCHEMBL12871956 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AHRH3POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |