SCHEMBL28293337

SCHEMBL28293337

Cc1ccccc1S(=O)(=O)N(C(N)=O)c1cccc(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
RORC P51449 1/20 0.40
TP53 P04637 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.38
PDE4B Q07343 1/20 0.38
HCRTR2 O43614 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
USP2 O75604 2/20 0.37
MAPT P10636 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
NSD2 O96028 1/20 0.36
ESR1 P03372 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28293334 0.85 TP53 (0.47) LMNATP53KDM4EHCRTR2KMT2A
SCHEMBL20981709 0.84 HCRTR2 (0.43) HCRTR2KMT2ANSD2ESR1POLB
SCHEMBL6326502 0.84 PARP1 (0.43) TP53HCRTR2KMT2AMAPTNSD2
SCHEMBL7601389 0.78 LMNA (0.44) LMNATP53SMN1; SMN2HCRTR2MAPT
SCHEMBL6331211 0.77 KCNA5 (0.43) TP53SMN1; SMN2HCRTR2KMT2AMEN1
SCHEMBL28295134 0.77 RORC (0.39) LMNARORCKDM4EHCRTR2KMT2A
SCHEMBL6244922 0.76 HCRTR2 (0.44) LMNAHCRTR2KMT2AMAPTNSD2
SCHEMBL28293341 0.75 TP53 (0.51) LMNATP53SMN1; SMN2KMT2AMAPT
SCHEMBL6329886 0.74 PARP1 (0.43) LMNARORCTP53HCRTR2KMT2A
SCHEMBL28295296 0.72 NPC1 (0.48) LMNATP53HCRTR2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790108-A Thermal recording medium 奥古斯特科勒纸厂欧洲公司 2019-05-21 CN disclosed